Toa Payoh - Junior Scientist, EDDC
Experimental Drug Development Centre (EDDC) is a drug discovery national platform in Singapore focused on translating upstream research into therapeutic assets to generate value for Singapore. EDDC is looking for a junior scientist to join the Computational Chemistry team to strengthen our efforts by leveraging Artificial Intelligence for small molecule drug discovery.
As part of the team, the candidate will be developing and applying cutting-edge computational methods such as generative AI for de novo molecular design toward diffrent classes of protein targets. The staff will also have opportunity to collaborate closely across functions, with biologists and chemists to support hit identification, hit-to-lead design, and lead optimization, with CADD scientists to develop machine learning models for in-house discovery programs.
Key Requirements- Bachelor degree in the field of chemistry/biology/computer science with good knowledge in drug discovery and design
- Ideal candidates should have expertise in at least one of the following: structure-based drug design, machine/deep learning model building and training
- Experience with machine learning algorithms (e.g. Random Forest, Support Vector Machine, Deep Neural Networks) and packages (e.g. Sci-kit Learn, Keras, TensorFlow, PyTorch) is a plus.
- Experience with one scripting or programming language (Python preferred) is preferred.
- Track record of applying machine learning, in particular modern deep learning approaches, to solve relevant biological or chemical problems is required.
- Personal attributes of independence, integrity, creativity, problem solving, and strong work ethic.
- Excellent communication skills.